COMPARE / MI300X VS MI350X
MI300X vs MI350X
Specs from the chip makers' datasheets; prices from the live Compute Cafe panel, refreshed hourly. Every rate is an on-demand published price with a source receipt.
CHEAPEST MI300X
$0.500/hr
RunPod · median $7.20 · 13 providers
CHEAPEST MI350X
$4.000/hr
CloudRift · median $4.00 · 1 providers
CHEAPER RIGHT NOW
MI300X
live panel, 2026-09-27
| MI300X | MI350X | |
|---|---|---|
| MAKER | AMD | AMD |
| ARCHITECTURE | CDNA 3 | CDNA 4 |
| LAUNCHED | 2023 | 2025 |
| MEMORY | 192 GB HBM3 | 288 GB HBM3E |
| MEMORY BANDWIDTH | 5.3 TB/s | 8 TB/s |
| TENSOR COMPUTE | 1,307 TFLOPS FP16/BF16 dense (2,614 sparse); 2,614 TFLOPS FP8 dense | 2.3 PFLOPS FP16/BF16 matrix (4.6 PFLOPS FP8, 9.2 PFLOPS MXFP4) |
| POWER DRAW | 750 W | 1,000 W (OAM, air-cooled; MI355X 1,400 W liquid) |
| INTERCONNECT | Infinity Fabric 896 GB/s | OAM (UBB), Infinity Fabric xGMI |
HOW TO CHOOSE
MI350X vs MI300X
The generational jump: 288 GB vs 192 GB, 8 vs 5.3 TB/s, and roughly 1.8x the FP16 matrix throughput (2.3 vs 1.3 PFLOPS class). Where MI350X rents near MI300X on the panel, it is the clear pick; the older chip wins only on availability and price.
Workload fit
MI300X: large-model inference, memory-bound training, cost-optimized clusters. MI350X: llm training, large-model inference, hpc.
MI300X VS MI350X - FAQ
Which is cheaper to rent, MI300X or MI350X?
By today's published on-demand rates: MI300X starts at $0.500/GPU/hr (median $7.20, 13 providers) and MI350X starts at $4.000/GPU/hr (median $4.00, 1 providers). The cheapest live listing is the MI300X at RunPod. Figures recompute from the panel on every refresh.
MI300X or MI350X - which should I rent?
MI300X: The MI300X is AMD's serious answer to Hopper: more memory (192 GB) and more bandwidth (5.3 TB/s) than any NVIDIA part before Blackwell, at panel prices that frequently undercut H100. MI350X: The MI350X is AMD's fourth-generation Instinct flagship: 288 GB of HBM3E at 8 TB/s with FP16 throughput at 2.3 PFLOPS, matching the MI355X's compute at a lower 1,000 W air-cooled power envelope. The side-by-side spec table and live price rows above give the full picture.
Where can I rent MI300X and MI350X?
13 providers publish MI300X rates and 1 publish MI350X rates on Compute Cafe. Every row links to the provider's own published price - committed-use and reserved rates are excluded.
Full pricing: MI300X · MI350X · all comparisons